February 2022 - Davis_members

Preorder now for Haschek and Rousseaux's Pinciples and Practice of Toxicologic Pathology.
by Bruce Williams Feb. 27, 2022

Feb. 27, 2022

It's not a Foundation publication, but the authors have all been great supporters, and some officers of the Foundation, so we are happy to give this one a boost! (Just don't expect Foundation pricing from Elsevier!) Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 1: Principles and Practice of Toxicologic Pathology - 4th Edition (elsevier.com ) https://www.elsevier.com/.../haschek/978-0-12-821047-5 <https://www.elsevier.com/books/haschek-and-rousseauxs-handbook-of-toxicolog…> Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 1: Principles and Practice of Toxicologic Pathology 4th Edition - October 20, 2021 Editors: Wanda Haschek, Colin Rousseaux, Matthew Wallig, Brad Bolon Hardcover ISBN: 9780128210444 eBook ISBN: 9780128218297 Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 1: Principles and Practice of Toxicologic Pathology The *Handbook of Toxicologic Patholog *has been extensively updated to continue its comprehensive and timely coverage. The 4th edition of *Haschek and Rousseaux’s Handbook of Toxicologic Pathology* has been expanded to 4 separate volumes due to unrelenting explosion of information in this field requiring new and updated chapters These volumes are being published separately. Volume 1, “Principles and the Practice of Toxicologic Pathology,” is now available and discussed in detail below. Volume 2, currently in press, encompasses “Toxicologic Pathology in Safety Assessment” and “Environmental Toxicologic Pathology”. These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4, currently in preparation, provide deep and broad treatment of “Target Organ Toxicity”, emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. Haschek and Rousseaux's Handbook of Toxicologic Pathology: Volume 1: Principles and Practice of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Volume 1 of the Fourth Edition covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Completely revised with a number of new chapters, Volume 1 of the Handbook of Toxicologic Pathology is an essential part of the authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Key Features - Provides new chapters on digital pathology, juvenile pathology, animal models, in vitro/in vivo correlation, big data technologies and in-depth discussion of timely topics in the area of toxicologic pathology - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations *Audience* Scientists, including pathologists, toxicologists and graduate students, in academia, industry and government. Potential settings include biopharmaceutical, medical device, and chemical companies; contract and basic research organizations; veterinary diagnostic laboratories and medical forensic laboratories; regulatory agencies and universities *Table of Contents* - Chapter 1. Toxicologic Pathology: An Introduction - Part 1. Principles of Toxicologic Pathology - Chapter 2. Biochemical and Molecular Basis of Toxicity - Chapter 3. ADME Principles in Small Molecule Drug Discovery and Development: An Industrial Perspective - Chapter 4. Biotherapeutics ADME and PK/PD Principles - Chapter 5. Principles of Pharmacodynamics and Toxicodynamics - Chapter 6. Morphologic Manifestations of Toxic Cell Injury - Chapter 7. The Role of Pathology in Evaluation of Reproductive, Developmental, and Juvenile Toxicity - Chapter 8. Carcinogenesis: Mechanisms and Evaluation - Part 2. Methods in Toxicologic Pathology - Chapter 9. Basic Approaches in Anatomic Toxicologic Pathology - Chapter 10. Clinical Pathology in Nonclinical Toxicity Testing - Chapter 11. Special Techniques in Toxicologic Pathology - Chapter 12. Digital Pathology and Tissue Image Analysis - Chapter 13. In Vivo Small Animal Imaging: A Comparison to Gross and Histopathologic Observations in Animal Models - Chapter 14. Biomarkers: Discovery, Qualification, and Application - Chapter 15. Toxicogenomics: A Primer for Toxicologic Pathologists - Chapter 16. Experimental Design and Statistical Analysis for Toxicologic Pathologists - Part 3. Animal and Alternative Models in Toxicologic Research - Chapter 17. Animal Models in Toxicologic Research: Rodents - Chapter 18. Animal Models in Toxicologic Research: Rabbit - Chapter 19. Animal Models in Toxicologic Research: Dog - Chapter 20. Animal Models in Toxicologic Research: Pig - Chapter 21. Animal Models in Toxicologic Research: Nonhuman Primate - Chapter 22. Animal Models in Toxicologic Research: Nonmammalian - Chapter 23. Genetically Engineered Animal Models in Toxicologic Research - Chapter 24. Alternative Models in Biomedical Research: In Silico, In Vitro, Ex Vivo, and Nontraditional In Vivo Approaches - Part 4. Practice of Toxicologic Pathology - Chapter 25. Nomenclature and Diagnostic Resources in Anatomic Toxicologic Pathology - Chapter 26. Pathology Peer Review - Chapter 27. Pathology and GLPs, Quality Control, and Quality Assurance - Chapter 28. Practices to Optimize Generation, Interpretation, and Reporting of Pathology Data from Toxicity Studies - Chapter 29. Issues in Laboratory Animal Science That Impact Toxicologic Pathology -- Bruce Williams Chief Financial Officer Davis-Thompson Foundation 301 467-4024 bruce.williams(a)davisthompsonfoundation.org www.davisthompsonfoundation.org

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Case submission deadline for NEVPC is coming soon!
by Bruce Williams Feb. 26, 2022

Feb. 26, 2022

2022 Northeastern Veterinary Pathology Conference (NEVPC) March 25 @ 9:00 am – March 26 @ 5:00 pm <https://davisthompsonfoundation.org/wp-content/uploads/2022/02/March-25-and…> Please join us virtually on March 25 (Friday), 9:00 am – 5:00 pm US EDT and March (Saturday) 26 9:00 am – 11:00 am US EDT for the 2022 NEVPC meeting, with a special focus on neuropathology. Registrants will have the opportunity to see a variety of curious cases (with an emphasis on neuropath) and to hear excellent keynote speakers. Dr. Jey Koehler (Auburn University) will share the state of the art information about canine meningiomas, and Dr. Andrew Miller (Cornell University) will address the classic and the new on equine neuropathology. You won’t want to miss this! Your registration will include access to the keynote speakers’ talks for 14 days. Case presentations will be LIVE only. This meeting is approved for 10 hours of RACE credits. If you would like to present a case, these slots will fill up fast, so contact course director Dr. Sarah Cudd at skcudddvm(a)gmail.com for details and diamond-hard deadlines. This year for the first time, We are also this year taking scanned slides as submissions in the following formats – Aperio (.svs), Hamamatsu (.vms, .vmu, or .ndpi), Leica (.scn), MIRAX (.mrxs), Philips (.tiff), Sakura (.svslide), Trestle (.tif), Ventana (.bif or .tif), or generic tiled TIFF (.tif) format. If you would like to participate as a non-presenting attendee (and get 10 hours of CE - what a deal!), you can register now at ($50): https://bit.ly/3sBOYUT -- Bruce Williams Chief Financial Officer Davis-Thompson Foundation 301 467-4024 bruce.williams(a)davisthompsonfoundation.org www.davisthompsonfoundation.org

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Clinical Instructor, Anatomic Pathology, Univ. of Wisconsin - Madison
by Bruce Williams Feb. 17, 2022

Feb. 17, 2022

*CLINICAL INSTRUCTOR IN ANATOMIC PATHOLOGY – * *UNIVERSITY OF WISCONSIN* The Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison seeks applicants for a *1-year position in Anatomic Pathology with a negotiable start date in the late summer or early fall of 2022 and potential for position renewal for up to three years.* This full-time position is designed to prepare the individual for Phase II of the ACVP certifying board examination and/or serve as a transitional position promoting growth and independence in individuals interested in a career in academia, for those exploring career options, or for those pursuing graduate studies at our institution. The successful applicant will have access to a diverse diagnostic caseload from the Veterinary Medical Teaching Hospital, Milwaukee County and Henry Vilas Zoos, International Crane Foundation, Wisconsin Department of Natural Resources, and specialty clinics, as well as the opportunity to collaborate with Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) pathologists in examining ocular biopsy specimens, participate in the professional DVM and resident instructional programs in anatomic pathology, and engage in collaborative research projects based on candidate interest. *Time off for ACVP certifying examination study is provided.* The School of Veterinary Medicine and Pathobiological Sciences Department offers the successful candidate the opportunity to join a dedicated team of 5 anatomic pathologists with diverse expertise and work in a collegial and supportive environment with exceptional resources in anatomic pathology, infectious disease pathobiology, oncology, food animal production medicine, and other disciplines. As a mid-sized city with a big-city energy, Madison offers diverse cultural and outdoor attractions locally and within a 2-hour drive. Applicants must possess the DVM/VMD or equivalent degree, be US citizens or permanent residents, have had *a minimum of 3 years anatomic pathology training and be eligible for Wisconsin licensure.* Since residency training at the University of Wisconsin-Madison School of Veterinary Medicine involves the practice of veterinary medicine on privately owned animals, the successful applicant would be required to be licensed in the state of Wisconsin at the start of the position. Details regarding qualification-based compensation and full benefits can be found in the University of Wisconsin job website listed below. Review of applications will begin immediately and deadline for receipt of applications for full consideration is *April 15th, 2022*. Application materials include a letter of intent and curriculum vitae to be submitted through: https://jobs.hr.wisc.edu/en-us/job/512236/clinical-instructor Please direct your three references to submit their letters of support to Matthew Oestreich, ATT: Anatomic Pathology Clinical Instructor Candidate at* pbs-admin(a)vetmed.wisc.edu <pbs-admin(a)vetmed.wisc.edu>*. If you have any questions regarding position details, please contact the Search Committee Chair, Dr. Sophie Aschenbroich, at aschenbroich(a)wisc.edu . The University of Wisconsin is an Equal Opportunity and Affirmative Action Employer. Minorities and women are strongly urged to apply. Names, titles and/or occupation, and addresses of applicants or nominees cannot be kept confidential.

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D-TF European Division Meeting: Non-human Primate Pathology...IN PERSON!
by Jey Koehler Feb. 16, 2022

Feb. 16, 2022

[A picture containing timeline Description automatically generated]Dear Foundation supporters, please mark your calendars for the 2022 Annual Symposium of the European Division of the Davis-Thompson Foundation on September 5&6 in Athens, Greece! The meeting is scheduled for IN PERSON, at the Sofitel, Athens International Airport. The symposium will be run in conjunction with the ESVP/ECVP annual meeting. This year’s speakers are: Dr. Anne Lewis (Oregon National Primate Research Center and Chair, ACVP Certifying Exam Board ) Dr. Amanda Beck (Albert Einstein College of Veterinary Medicine, NY) This two-day course of 11 hours of lectures plus interactive case discussions is aimed at pathologists and trainees and especially those studying for RCPath or ACVP and ECVP board exams. Topics include: * Infectious and non-infectious diseases of non-human primates * Macaques * New World primates (squirrel and owl monkeys and marmosets) * Baboons and Chimpanzees * NHP Placental and Peri-natal pathology * Juvenile histology * Spontaneous genetic diseases of NHP as human models * Pathology of aging in NHPs REGISTRATION The course fee is €329.00 until 30th June 2022 and €379 from 1st July 2022. Registration closes 3 days before the event. The fees include meeting registration, electronic notes, lunch, and refreshment breaks on both days, and an evening reception on the first day. For more information and to register, please visit https://davisthompsonfoundation.org/event/2022-annual-symposium-of-the-euro… Jey Koehler, DVM, PhD, Dipl. ACVP Auburn University Department of Pathobiology President, Davis-Thompson Foundation www.davisthompsonfoundation.org<http://www.davisthompsonfoundation.org/> [cid:image001.png@01D8233D.AD466A80]

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DTF-LCPG 183- Question Sheet
by claudio barros Feb. 15, 2022

Feb. 15, 2022

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DTF-LCPG #182 - Answer Sheet
by claudio barros Feb. 15, 2022

Feb. 15, 2022

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Hearts for Valentine's Day!
by Jey Koehler Feb. 10, 2022

Feb. 10, 2022

[cid:image002.png@01D81E94.508F6EC0]Do you have a crush on cardiovascular pathology? Does it make your little heart go thump-thump? Well get ready for a fantastic full day of cardiovascular pathology with four outstanding speakers! Please be our belated Valentine on February 22, 2022 from 9:00am to 4:00pm US Central Standard time for a full-day seminar dedicated to the subject. Participants will be able to learn more about cardiac evaluation; heart disease in great apes; how to approach sudden death cases; congenital anomalies; basic approaches for gross cardiovascular device assessment and histology of cardiovascular devices; and much more! Registration is $50. Don't forget, registrants will get access to the recorded seminar for 14 days in case you can't watch it in real-time. [cid:image003.png@01D81E94.508F6EC0]For more information and to register, please visit https://davisthompsonfoundation.org/event/cardiovascular-pathology/ We would LOVE to see you there! Jey Koehler, DVM, PhD, Dipl. ACVP Auburn University Department of Pathobiology President, Davis-Thompson Foundation www.davisthompsonfoundation.org<http://www.davisthompsonfoundation.org/> [cid:image001.png@01D81E93.15E42A50]

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Davis-Thompson Foundation Photo Contest
by Katherine D. Watson Feb. 7, 2022

Feb. 7, 2022

They say a picture is worth a thousand words. Do you have a noteworthy photo that you want to share with an international community dedicated to the advancement of veterinary and comparative pathology? Each month we highlight a photo on the cover of the Davis-Thompson Foundation Newsletter, and we hope to feature your work in the next issue! Submission information (see attached document for complete file requirement details): * Submission deadline: The 15th of each month to be considered for the upcoming issue * Send your image by e-mail to: * Dr. Watson: images(a)davisthompsonfoundation.org<mailto:images@davisthompsonfoundation.org> Figure Requirements (see examples below): * Do not exceed maximum file size of 5 MB. * Width of the image should be 6.8 inches. * Acceptable formats are TIFF and JPEG (TIFF preferred) Figure Legend (attach as a word document separated from the image file): * Name/names of contributors and their affiliated institutions * Brief (no longer than 2 sentence) description of the lesion including: * Signalment * Diagnosis * Any other pertinent information you want to share Cheers, Kate Watson, DVM PhD DACVP California Animal Health and Food Safety Laboratory Assistant Professor of Anatomic Pathology "Mortui vivos docent" <http://www.vetmed.ucdavis.edu/research/grad_education/vstp/index.cfm> Publication List<http://scholar.google.com/citations?user=cGQfYQoAAAAJ&hl=en> "I know quite certainly that I myself have no special talent. Curiosity, obsession and dogged endurance, combined with self-criticism, have brought me to my ideas." - Albert Einstein

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comparative Pathologist Opening, Penn Comparative Pathology Core
by Bruce Williams Feb. 5, 2022

Feb. 5, 2022

Comparative Pathologist Penn Vet Comparative Pathology Core, School of Veterinary Medicine, University of Pennsylvania, USA Job Description: The Penn Vet Comparative Pathology Core (CPC) at the University of Pennsylvania, School of Veterinary Medicine, invites applications for a research fellow position in experimental and comparative pathology. The CPC is an established core facility within the Department of Pathobiology and a fully integrated shared resource within the NIH/NCI-funded Abramson Cancer Center since 2015. The main objective of the CPC is to provide expert pathological characterization of experimental animal models to fulfill the growing needs of the local biomedical community performing in vivo studies as part of their basic and translational research endeavors. In this context, the CPC plays a vital role as it supports several major research programs within the University of Pennsylvania and closely related institutes such as the Abramson Cancer Center, the Children's Hospital of Philadelphia, and the Wistar Institute. To accomplish its mission, the CPC offers the expertise of board-certified veterinary pathologists and access to a state-of-the-art platform for histology services, molecular staining of tissue samples, and digital pathology. This position will primarily contribute to the mission of the CPC by providing expertise in experimental and comparative pathology. Main responsibilities and duties include: • Expert interpretation of pathological endpoints in the context of diverse preclinical/experimental settings with accurate and timely reporting of pathological findings. While humanized and genetically engineered mice represent the majority of the caseload, studies using rats, dogs, non-human primates, sheep, and pigs are also frequently performed. • Interaction with scientists and investigators to design experiments, discuss results and plan follow-up studies as pertain to the specific research context. • Provide guidance to investigators, students, and laboratory technicians in all those activities and techniques related to comparative pathology (e.g., necropsy, sample preparation, development of multiparametric histopathological scoring system, digital image analysis, etc.). • Contribute to the general management and supervision of routine laboratory activities/services. • Contribute to the teaching/training of veterinary pathology residents and veterinary students rotating with the CPC. This position represents a unique opportunity for candidates who want to deepen their understanding of comparative pathology applied to the most innovative aspects of translational research including the study of in vivo models for cellular therapies (e.g., CAR T cells and stem cells). While the primary role of this position is to support the service activities of the CPC, the program offers ample opportunity to carry out independent projects focused on developing accurate clinicopathological strategies to assess the phenotype of new and existing experimental animal models Qualifications: Applicants should have a DVM/VMD and be board-eligible or board-certified in Anatomic Pathology by the American, European, or Japanese College of Veterinary Pathologists; experience with rodent pathology and digital image analysis is desirable. The salary will be commensurate with the applicant’s qualifications, training, and experience. The application deadline is June 4, 2022, or until the position is filled. Review of applications will begin immediately and continue until a suitable candidate is found. Application Instructions: To apply for this position, please send cover letter, curriculum vitae, and the names and contacts of 3 references to the following email address: comppathologycore(a)vet.upenn.edu Further information on the position can be obtained by contacting Dr. Enrico Radaelli, Director of the Comparative Pathology Core, enrada(a)vet.upenn.edu To learn more about the Penn Vet Comparative Pathology Core: https://www.vet.upenn.edu/research/core-resources-facilities/comparative-pa… -- Bruce Williams Chief Financial Officer Davis-Thompson Foundation 301 467-4024 bruce.williams(a)davisthompsonfoundation.org www.davisthompsonfoundation.org

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Open anatomic pathology residency position, University of Wisconsin at Madison
by Bruce Williams Feb. 4, 2022

Feb. 4, 2022

RESIDENCY IN ANATOMIC PATHOLOGY – UNIVERSITY OF WISCONSIN The Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison welcomes applicants for a 3-year training position in Anatomic Pathology effective July 1, 2022. This position is designed to prepare the individual for the ACVP certifying board examination and is based on a diverse diagnostic caseload from a wide array of sources, such as the UW Veterinary Medical Teaching Hospital, Milwaukee County and Henry Villas Zoos, International Crane Foundation, Wisconsin DNR, and specialty clinics. The successful candidate will also be exposed to the large-volume caseload of the UW RARC Comparative Pathology Laboratory and have the opportunity to collaborate extensively with Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) pathologists during the examination of ocular biopsies. Additional training opportunities include active participation in diverse rounds and in the instructional program in Anatomic Pathology, as well as engaging in collaborative research projects based on candidate interest. The Pathobiological Sciences Department offers the successful candidate the opportunity to join a dedicated team of 5 anatomic pathologists with diverse expertise, in a collegial and supportive environment with exceptional resources in anatomic pathology, infectious disease pathobiology, oncology, food animal production medicine, and other disciplines. For a more detailed overview of our anatomic pathology training program, please visit: https://d34y695x0pxlvj.cloudfront.net/wp-content/uploads/2021/06/anat_path_… Applicants must possess the DVM/VMD or equivalent degree and be eligible for Wisconsin licensure. Since residency training at the University of Wisconsin-Madison School of Veterinary Medicine involves the practice of veterinary medicine on privately owned animals, the successful applicant would be required to be licensed in the state of Wisconsin at the start of the position. Please note that applications are restricted to US citizens, foreign residents, and to individuals with specific visas, such as TN or E. Unfortunately, H1B visa applicants cannot be accepted at this time. Applications consist of a (1) letter of intent, (2) curriculum vitae submitted by the candidate as well as (3) three letters of recommendation submitted by the referring individuals. To apply or for related questions, please email Dr. Sophie Aschenbroich at aschenbroich(a)wisc.edu. Applications will be reviewed upon receipt and will be considered until February 28, 2022. The University of Wisconsin is an Equal Opportunity and Affirmative Action Employer. Minorities and women are strongly urged to apply. Names, titles and/or occupation, and addresses of applicants or nominees cannot be kept confidential. -- Bruce Williams Chief Financial Officer Davis-Thompson Foundation 301 467-4024 bruce.williams(a)davisthompsonfoundation.org www.davisthompsonfoundation.org

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