Dear All, The Question Sheet for Diagnostic Exercise #259, contributed by Erin Schwalbe, Matias Dorsch, and Jose Cesar Menk*, is attached. Department of Pathobiological Sciences and Louisiana Animal Disease Diagnostic Laboratory, Louisiana State University School of Veterinary Medicine, Baton Rouge, LA. *Corresponding author: cmenk2@lsu.edu Best Regards Claudio The Diagnostic Exercises are an initiative of the Latin Comparative Pathology Group (LCPG), the Latin American subdivision of The Davis-Thompson Foundation. Members and non-members from any country of residence may contribute to these exercises. Please consider contributing a case to this initiative. It does not have to be unusual, and all pathology sub-specialties are welcome! Please consult instructions on how to format and submit your DE at https://davisthompsonfoundation.org/diagnostic-exercises-instructions/ Previous cases are available at https://davisthompsonfoundation.org/diagnostic-exercise/