Dear All, I've attached the Question sheet for Diagnostic Exercise #250, which was contributed by Anderson H. Gris1, Paola Sônego1, Emanoelly M. S. Silva1, Claudio S. L. Barros2, and David Driemeier1. 1Setor de Patologia Veterinária, Faculdade de Medicina Veterinária, Universidade Federal do Rio Grande do Sul (SPV-UFRGS), Porto Alegre, RS, Brazil. 2Laboratório de Anatomia Patológica, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil. Corresponding author: anderson_gris@hotmail.com.br Best Regards Claudio The Diagnostic Exercises are an initiative of the Latin Comparative Pathology Group (LCPG), the Latin American subdivision of The Davis-Thompson Foundation. These exercises are contributed by members and non-members from any country of residence. Please consider contributing a case to this initiative. It does not have to be unusual, and all sub-specialties of pathology are welcome! Please consult instructions on how to format and submit your DE at https://davisthompsonfoundation.org/diagnostic-exercises-instructions/ Previous cases are available at https://davisthompsonfoundation.org/diagnostic-exercise/